ncRNA name | hsa-miR-204 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples and para-carcinoma normal tissues; RB cell lines Y79 and HXO-RB44; human retinal microvascular endothelial cell line ACBRI-181 |
Methods | transfection, qRT-PCR, MTT assay |
Expression pattern | down-regulated |
Functional description | miR-204 may inhibit proliferation and promote apoptosis of RB cells through downregulating the expression of Bcl-2 and Sirt1 in RB. |
PubMed ID | 30546451 |
Year | 2018 |
Title | Expression of miR-204 in pediatric retinoblastoma and its effects on proliferation and apoptosis of cancer cells. |
Drug-related ncRNA | NO |
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